One of the most basic and important sectors of agricultural biotechnology is tissue culture, which is the method of a sexual reproduction in absolutely sterile conditions. In this technology usually a part of the plant called explant which is plated in the sterile and artificial condition in a culture medium and in a short time a large number of plants as rootstock are produced. In the plants with the mass reproduction trouble using of this technology can overcome the difficulties and increase their reproduction. The main aim of this department is development of protocols for micropropagation of fruit trees and mass production using different tissue culture methods.